Dr. Lynch began her research career as a Physics graduate student at the University of Pennsylvania while pursuing a PhD in the field of biomedical optics. During graduate school, she began collaborating with clinicians at the Children’s Hospital of Philadelphia to use novel optical neuromonitoring devices in children with congenital heart disease to predict risk of neurologic injury. After graduate school, she decided to enroll in medical school and obtain clinical training in pediatric cardiac anesthesiology to continue this work. Dr. Lynch is currently a pediatric cardiac anesthesiologist at CHOP and assistant professor at the University of Pennsylvania Perelman School of Medicine with a dual appointment in the Department of Bioengineering in the UPenn School of Engineering and Applied Sciences. Dr. Lynch has several philanthropic and internal grants to support her research while she works towards NIH funding as an early-stage investigator. Her work continues to center on the development and use of novel neuromonitoring devices to improve detection of periods of neurologic risk in congenital heart disease.
Lab url: https://www.research.chop.edu/lynch-lab-for-novel-biomedical-optics
PI url: https://www.research.chop.edu/people/jennifer-m-lynch
Email: [email protected]
Select publications:
Shaw K, Mavroudis CD, Ko TS, Jahnavi J, Jacobwitz M, Ranieri N, Forti RM, Melchior RW, Baker WB, Yodh AG, Licht DJ, Nicolson SC, Lynch JM. The use of novel diffuse optical spectroscopies for improved neuromonitoring during neonatal cardiac surgery requiring antegrade cerebral perfusion. Frontiers in Pediatrics. 2023;11.
Lynch JM, Mavroudis CD, Ko TS, Jacobwitz M, Busch DR, Xiao R, Nicolson SC, Montenegro LM, Gaynor JW, Yodh AG, Licht DJ, Association of ongoing cerebral oxygen extraction during deep hypothermic circulatory arrest with post-operative brain injury. Seminars in Thoracic and Cardiovascular Surgery. 2021.
Lynch JM, Ko T, Busch DR, Newland JJ, Winters ME, Mensah-Brown K, Boorady TW, Xiao R, Nicolson SC, Montenegro LM, Gaynor JW, Spray TL, Yodh AG, Naim MY, Licht DJ. “Pre-Operative Cerebral Hemodynamics from Birth to Surgery in Neonates with Critical Congenital Heart Disease.” The Journal of Thoracic and Cardiovascular Surgery. 2018;156(4):1657-1664.
Lynch JM, Buckley EM, Schwab PJ, McCarthy AL, Winters ME, Busch DR, Xiao R, Nicolson SC, Montenegro LM, Fuller S, Gaynor JW, Spray TL, Yodh AG, Naim MY, Licht DJ. “Time to surgery and preoperative cerebral oxygenation predict postoperative ischemic injury in hypoplastic left heart syndrome.” The Journal of Thoracic and Cardiovascular Surgery. 2014;148(5):2181-2188.
Koichi Yuki, MD
Immunology Research Laboratory | The Yuki Lab
KOICHI YUKI, M.D is PI of Yuki Lab, Dept of Immunology, Harvard Medical School. He is also a pediatric cardiac anesthesiologist at Boston Children’s Hospital. His research focuses on myeloid cells and systemic inflammation and anesthetics on perioperative immune function and postoperative outcomes.