Question of the Week 498

{“questions”:{“wnlk5”:{“id”:”wnlk5″,”mediaType”:”image”,”answerType”:”text”,”imageCredit”:””,”image”:””,”imageId”:””,”video”:””,”imagePlaceholder”:””,”imagePlaceholderId”:””,”title”:”Author: Melissa Colizza, MD – Stollery Children\u2019s Hospital – Edmonton, Canada \r\nA 25-year-old, G2P0 woman at 28 weeks gestation presents with three-pillow orthopnea. A transesophageal echocardiogram reveals severe mitral stenosis, which will require mitral valve replacement surgery. What is the expected maternal mortality after mitral valve replacement?\r\n\r\n”,”desc”:”EXPLANATION \r\nCardiovascular disease has become increasingly common during pregnancy […]

Question of the Week 497

{“questions”:{“wfi6c”:{“id”:”wfi6c”,”mediaType”:”image”,”answerType”:”text”,”imageCredit”:””,”image”:””,”imageId”:””,”video”:””,”imagePlaceholder”:””,”imagePlaceholderId”:””,”title”:”Authors: Kaitlin M. Flannery, MD, MPH – Stanford University AND Amy Babb MD – Monroe Carell Jr. Children\u2019s Hospital, Vanderbilt \r\n\r\nAn eight-month-old boy with a history of Williams syndrome underwent repair of supravalvar aortic stenosis 24 hours ago. The blood pressure is noted to be 124\/84 despite administration of additional analgesic and sedative medications. The […]

Question of the Week 496

{“questions”:{“akel6”:{“id”:”akel6″,”mediaType”:”image”,”answerType”:”text”,”imageCredit”:””,”image”:””,”imageId”:””,”video”:””,”imagePlaceholder”:””,”imagePlaceholderId”:””,”title”:”Author: Melissa Colizza, MD – Stollery Children\u2019s Hospital -Edmonton AB Canada \r\n\r\nA 1-week-old girl with severe pulmonary stenosis, intact ventricular septum, and moderate tricuspid valve regurgitation is status post balloon pulmonary valvuloplasty. Two hours later, the heart rate was 188, with an arterial blood pressure of 46\/19 and oxygen saturation of 88%. A transthoracic echocardiogram […]

Question of the Week 495

{“questions”:{“cw7s2”:{“id”:”cw7s2″,”mediaType”:”image”,”answerType”:”text”,”imageCredit”:””,”image”:””,”imageId”:””,”video”:””,”imagePlaceholder”:””,”imagePlaceholderId”:””,”title”:”Author: Melissa Colizza, MD – Stollery Children\u2019s Hospital, Edmonton Canada \r\nA 15-month-old boy is started on a bivalirudin infusion after placement of a Berlin Heart ventricular assist device. Which of the following tests is MOST frequently used to monitor anticoagulation with bivalirudin? \r\n\r\n”,”desc”:”EXPLANATION \r\nBivalirudin is a direct thrombin inhibitor (DTI) that exerts its anticoagulant effect […]

Question of the Week 494

{“questions”:{“6i5h4”:{“id”:”6i5h4″,”mediaType”:”image”,”answerType”:”text”,”imageCredit”:””,”image”:””,”imageId”:””,”video”:””,”imagePlaceholder”:””,”imagePlaceholderId”:””,”title”:”Author: Melissa Colizza, MD – Stollery Children’s Hospital, University of Alberta, Edmonton, Canada\r\n\r\nA 5-month-old girl with Noonan syndrome and confirmed RIT1 mutation presents with failure to thrive. A transthoracic echocardiogram demonstrates biventricular hypertrophy with a peak subaortic gradient of 88 mmHg. Which of the following medications is MOST likely to produce regression of the underlying […]